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Minimally clinically significant. Reduce hazard; evaluate risk and consider an alternate drug, choose methods to avoid the interaction hazard and/or institute a monitoring system.

Individuals that use massive quantities of cannabis may possibly become sedated or disoriented and should experience toxic psychosis -- not being aware of who These are, where They may be, or what time it is actually.

irritation on the lungs, danger of acquiring chronic bronchitis and an increased danger of producing most cancers of your respiratory tract (more likely to carry out with smoking).

The cannabinoid compounds located in these synthetic brokers act within the same mobile receptors as People afflicted via the THC in purely natural marijuana. Determined compounds include2:

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THC from marijuana functions on unique receptors while in the Mind, referred to as cannabinoid receptors, starting off a sequence of mobile reactions that at last produce the euphoria, or "high" that end users experience. Activation of your endocannabinoid system brings about the discharge of dopamine, a neurotransmitter connected Using the reward program.

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